ATP1A1

Across TCGA cell cohorts, ATP1A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,599 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible ATP1A1-associated GO terms across cancer lineages are Response to glycoside, Fungiform papilla development, and Fungiform papilla morphogenesis. Each is linked with ATP1A1 in more than 11 cancer types. Because this analysis shows association rather than direction, both ATP1A1-to-partner and partner-to-ATP1A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to glycoside grouped by ATP1A1-low versus ATP1A1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP1A1→partner) and Y-score (partner→ATP1A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Response to glycoside →	+0.156	+1.055	<.001	<.001	3	12
STOMACH	Fungiform papilla development →	+0.179	+1.045	.006	.003	3	8
STOMACH	Fungiform papilla morphogenesis →	+0.179	+1.045	.006	.003	3	8
SKIN	ADP metabolic process →	+0.096	+1.108	<.001	<.001	3	8
SOFT_TISSUE	Biological process involved in symbiotic interaction →	+0.078	+0.778	<.001	.001	3	8
SKIN	Multi-pass transmembrane protein insertion into ER membrane →	+0.120	+1.201	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,599 associations by consensus.

Response to glycoside by ATP1A1 expression — SOFT_TISSUE

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