ATP13A5

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ATP13A5 mutation is significantly associated with the total protein of many other genes, with 51 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATP13A5-associated genes across cancer lineages are INPP4B, eEF2, and Annexin-1. Each is linked with ATP13A5 in more than 2 cancer types. Because this analysis shows association rather than direction, both ATP13A5-to-partner and partner-to-ATP13A5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP13A5→partner) and Y-score (partner→ATP13A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECINPP4B →-0.292-2.999.003<.00133
UCECeEF2 →+0.245+1.700.027.04032
UCECAnnexin-1 →+0.350+1.505.032.03432
UCECShc_pY317 →-0.170-1.736<.001.00632
UCECTFRC →+0.478+2.115.003.01632
COADMIG-6 →+0.124+2.866.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 51 associations by consensus.

Exploration