ATP13A5

mutation — cross-omics
Cross-omicsMUTATION → RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, ATP13A5 mutation is significantly associated with the RNA expression of many other genes, with 549 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ATP13A5-associated genes across cancer lineages are KCTD1, OR1J1, and CLPS. Each is linked with ATP13A5 in more than 2 cancer types. Because this analysis shows association rather than direction, both ATP13A5-to-partner and partner-to-ATP13A5 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP13A5→partner) and Y-score (partner→ATP13A5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LARGE_INTESTINEKCTD1 →+0.933+2.743.003.00133
SOFT_TISSUEOR1J1 →+0.098+4.321<.001<.00132
SOFT_TISSUECLPS →+0.076+3.977<.001.00732
SOFT_TISSUESMR3B →+0.696+3.142<.001.00832
BLOOD_MyelomaCDH16 →+0.032+3.584.001.00732
BLOOD_LeukemiaPHOX2B →+0.012+3.102.003.00232
Each partner links to its Q-omics profile. Showing the 6 strongest of 549 associations by consensus.

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