ATP13A4

Across TCGA patient cohorts, ATP13A4 protein abundance is significantly associated with the RNA expression of many other genes, with 10,624 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ATP13A4-associated genes across cancer lineages are ATP13A4-AS1, POFUT2, and GINS1. Each is linked with ATP13A4 in more than 3 cancer types. Because this analysis shows association rather than direction, both ATP13A4-to-partner and partner-to-ATP13A4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATP13A4 versus ATP13A4-AS1 in LUAD, with a Pearson correlation of 0.62.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP13A4→partner) and Y-score (partner→ATP13A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	ATP13A4-AS1 →	+1.942	+0.673	<.001	<.001	3	4
PDAC	POFUT2 →	+0.640	+0.640	.002	.002	3	3
LUAD	GINS1 →	-0.779	-0.462	<.001	<.001	3	3
GBM	GTPBP4 →	-0.378	-0.479	<.001	<.001	3	3
GBM	SMC3 →	-0.446	-0.442	.001	.002	3	3
LUAD	RAD51AP1 →	-1.048	-0.666	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,624 associations by consensus.

ATP13A4 vs ATP13A4-AS1 — LUAD

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