ATP13A4

Across TCGA cell cohorts, ATP13A4 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,187 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ATP13A4-associated GO terms across cancer lineages are Regulation of cytoplasmic translation, Foam cell differentiation, and Fertilization. Each is linked with ATP13A4 in more than 6 cancer types. Because this analysis shows association rather than direction, both ATP13A4-to-partner and partner-to-ATP13A4 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of cytoplasmic translation grouped by ATP13A4-low versus ATP13A4-high in OVARY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP13A4→partner) and Y-score (partner→ATP13A4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of cytoplasmic translation →	+0.105	+0.289	<.001	.004	3	7
BREAST	Foam cell differentiation →	-0.288	-1.076	.005	.001	3	6
OVARY	Fertilization →	-0.089	-0.301	<.001	.006	3	6
SOFT_TISSUE	Astrocyte development →	+0.090	+0.125	.001	<.001	3	6
OVARY	Alternative mRNA splicing, via spliceosome →	+0.109	+0.203	<.001	.001	2	7
OESOPHAGUS	Aerobic electron transport chain →	+0.113	+0.713	.002	.009	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,187 associations by consensus.

Regulation of cytoplasmic translation by ATP13A4 expression — OVARY

Explore this box plot interactively →