ATP13A3

Across TCGA cell cohorts, ATP13A3 mutation is significantly associated with the RNA expression of many other genes, with 143 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ATP13A3-associated genes across cancer lineages are OR11H6, OR4K1, and KRTAP5-11. Each is linked with ATP13A3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATP13A3-to-partner and partner-to-ATP13A3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR11H6 grouped by ATP13A3-low versus ATP13A3-high in CNS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP13A3→partner) and Y-score (partner→ATP13A3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CNS	OR11H6 →	+0.026	+4.321	<.001	.009	3	1
LUNG_NSCLC_LUAD	OR4K1 →	+0.019	+5.228	<.001	.005	3	1
LUNG_NSCLC_LUAD	KRTAP5-11 →	+0.111	+4.887	<.001	.009	3	1
LUNG_NSCLC_LUAD	PRAMEF5 →	+0.043	+5.228	<.001	.005	3	1
OVARY	TAS1R2 →	+0.017	+3.700	<.001	.005	3	1
BLOOD_Leukemia	OR5P3 →	+0.125	+5.201	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 143 associations by consensus.

OR11H6 by ATP13A3 expression — CNS

Explore this box plot interactively →