ATP13A1

Across TCGA cell cohorts, ATP13A1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,012 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ATP13A1-associated GO terms across cancer lineages are Positive regulation of T-helper 17 cell lineage commitment, Regulation of transcription of nucleolar large rRNA by RNA polymerase I, and Positive regulation of transcription of nucleolar large rRNA by RNA polymerase I. Each is linked with ATP13A1 in more than 13 cancer types. Because this analysis shows association rather than direction, both ATP13A1-to-partner and partner-to-ATP13A1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of T-helper 17 cell lineage commitment grouped by ATP13A1-low versus ATP13A1-high in KIDNEY.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP13A1→partner) and Y-score (partner→ATP13A1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
KIDNEY	Positive regulation of T-helper 17 cell lineage commitment →	+0.207	+0.853	.004	.003	3	14
BONE	Regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.159	+0.763	.001	.008	3	13
CNS	Positive regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.163	+0.758	<.001	<.001	3	13
STOMACH	Positive regulation of double-strand break repair →	+0.078	+0.740	.008	.001	3	13
BONE	Subtelomeric heterochromatin formation →	+0.172	+1.216	<.001	<.001	3	13
BLOOD_Lymphoma	Regulation of DNA repair →	+0.052	+1.024	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,012 associations by consensus.

Positive regulation of T-helper 17 cell lineage commitment by ATP13A1 expression — KIDNEY

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