ATP11C

Across TCGA cell cohorts, ATP11C RNA expression is significantly associated with the go_rna of many other GO terms, with 4,913 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ATP11C-associated GO terms across cancer lineages are Nuclear pore complex assembly, Nuclear pore organization, and Regulation of cell cycle G2/M phase transition. Each is linked with ATP11C in more than 10 cancer types. Because this analysis shows association rather than direction, both ATP11C-to-partner and partner-to-ATP11C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear pore complex assembly grouped by ATP11C-low versus ATP11C-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATP11C→partner) and Y-score (partner→ATP11C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Nuclear pore complex assembly →	+0.113	+1.462	.001	.001	3	11
BONE	Nuclear pore organization →	+0.157	+1.842	<.001	<.001	3	11
LUNG_SCLC	Regulation of cell cycle G2/M phase transition →	+0.067	+1.498	<.001	.002	3	10
BLOOD_Leukemia	Subtelomeric heterochromatin formation →	+0.102	+0.892	<.001	<.001	3	10
SKIN	mRNA export from nucleus →	+0.079	+0.744	.001	.001	3	10
LARGE_INTESTINE	Mitochondrial DNA repair →	+0.088	+0.945	.001	.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,913 associations by consensus.

Nuclear pore complex assembly by ATP11C expression — LUNG_SCLC

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