Across TCGA pan-cancer cohorts, ATP11AUN RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated ATP11AUN data layer compared with 3 for mutation status.
The strongest signal is observed in adrenocortical carcinoma (ACC), where higher ATP11AUN RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated ATP11AUN expression acts as an unfavorable survival marker, although some lineages such as KIRC and UVM show a favorable association.
ACC, KIRC, and UVM are the cancer types where ATP11AUN RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.