ATOX1

Across TCGA pan-cancer cohorts, ATOX1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated ATOX1 data layer compared with 20 for mass-spec protein.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher ATOX1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated ATOX1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and PDAC show a favorable association.

UCEC, LSCC, and COAD are the cancer types where ATOX1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	III,IV	1.000	0.449	.010	8	view →
LSCC	OS	Quartile	II,III,IV	0.600	0.941	.009	8	view →
COAD	DFS	Median	III,IV	0.835	1.000	.033	6	view →
CCRCC	DFS	Quartile	III,IV	0.514	0.972	.020	4	view →
PDAC	OS	Median	All	0.514	0.283	.020	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

ATOX1–UCEC (OS)

Open the UCEC breakdown →