ATOH1

Across TCGA cell cohorts, ATOH1 mutation is significantly associated with the RNA expression of many other genes, with 7 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ATOH1-associated genes across cancer lineages are R3HDML, BANF2, and C1orf87. Each is linked with ATOH1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATOH1-to-partner and partner-to-ATOH1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, R3HDML grouped by ATOH1-low versus ATOH1-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATOH1→partner) and Y-score (partner→ATOH1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	R3HDML →	+0.006	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	BANF2 →	+0.047	+5.643	<.001	.002	3	1
BLOOD_Lymphoma	C1orf87 →	+0.056	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	OR1M1 →	+0.019	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	OR9A2 →	+0.018	+5.209	<.001	.005	3	1
LARGE_INTESTINE	ACSM6 →	+0.027	+4.584	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 7 associations by consensus.

R3HDML by ATOH1 expression — BLOOD_Lymphoma

Explore this box plot interactively →