ATL3

Mutation & survival
SurvivalMutationKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, ATL3 Mutation is linked to patient survival in 7 of 34 cancer types, making it a survival-associated ATL3 data layer compared with 18 for mass-spec protein and 5 for mass-spec protein.

The strongest signal is observed in stomach adenocarcinoma (STAD), where higher ATL3 Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated ATL3 expression acts as an unfavorable survival marker.

STAD, COAD, and LIHC are the cancer types where ATL3 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
STADOSMedianIII,IV0.0010.633<.00124view →
COADOSMedianII,III,IV0.1330.853<.00124view →
LIHCOSMedianII,III,IV0.2040.715.0169view →
LUADDFSMedianAll0.2060.767.0069view →
BLCADFSMedianIII,IV0.1000.572.0016view →
UCECOSMedianIV0.2310.592.0366view →
LUSCOSMedianAll0.1920.724.0403view →
Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

Exploration