ATL3

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ATL3 mutation is significantly associated with the RNA expression of many other genes, with 1,644 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATL3-associated genes across cancer lineages are CST12P, RNU6-927P, and MIR3118-3. Each is linked with ATL3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATL3-to-partner and partner-to-ATL3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATL3→partner) and Y-score (partner→ATL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCCST12P →+0.206+5.736<.001.00332
BLCARNU6-927P →+0.520+5.106<.001.00832
BRCAMIR3118-3 →+0.558+8.471<.001.00531
HNSCNF1P5 →+0.272+5.822<.001.00331
HNSCOR14C36 →+0.211+6.339<.001.00131
HNSCSCGB1D4 →+0.318+5.435<.001.00531
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,644 associations by consensus.

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