Across TCGA patient cohorts, ATL3 mutation is significantly associated with the total protein of many other genes, with 28 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATL3-associated genes across cancer lineages are eEF2, ER-alpha_pS118, and A-Raf_pS299. Each is linked with ATL3 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATL3-to-partner and partner-to-ATL3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATL3→partner) and Y-score (partner→ATL3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eEF2 →	+0.330	+2.999	.029	.035	3	1
UCEC	ER-alpha_pS118 →	-0.304	-2.222	.046	.011	3	1
UCEC	A-Raf_pS299 →	-0.129	-3.321	.010	.009	3	1
UCEC	GAPDH →	+0.476	+3.169	.036	.018	3	1
UCEC	JNK_pT183_Y185 →	-0.190	-2.000	.007	.030	3	1
UCEC	Ku80 →	+0.224	+1.713	.025	.027	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 28 associations by consensus.

Exploration

ATL3 survival (RNA) · tumor vs normal (RNA) · all ATL3 data types