ATL2

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ATL2 protein abundance is significantly associated with the RNA expression of many other genes, with 16,162 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ATL2-associated genes across cancer lineages are CPED1, SCML4, and RASGRP2. Each is linked with ATL2 in more than 6 cancer types. Because this analysis shows association rather than direction, both ATL2-to-partner and partner-to-ATL2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATL2 versus CPED1 in LSCC, with a Pearson correlation of -0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATL2→partner) and Y-score (partner→ATL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCCPED1 →-0.899-0.466<.001<.00137
HNSCSCML4 →-0.866-0.388<.001<.00136
LSCCRASGRP2 →-0.788-0.392<.001<.00136
HNSCCD40LG →-0.769-0.475<.001<.00135
OVCD37 →-0.994-0.422<.001<.00135
OVCARD8 →-0.596-0.412<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 16,162 associations by consensus.

ATL2 vs CPED1 — LSCC

Per-sample scatter of ATL2 vs CPED1 in LSCC (Pearson r = -0.41).

Explore this scatter interactively →

Exploration