ATL2

Across TCGA cell cohorts, ATL2 mutation is significantly associated with the RNA expression of many other genes, with 14 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ATL2-associated genes across cancer lineages are SLC5A1, CCDC54, and NLRP8. Each is linked with ATL2 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATL2-to-partner and partner-to-ATL2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC5A1 grouped by ATL2-low versus ATL2-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATL2→partner) and Y-score (partner→ATL2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	SLC5A1 →	+0.034	+2.906	.001	.008	3	1
BLOOD_Lymphoma	CCDC54 →	+0.185	+3.509	<.001	.008	3	1
BLOOD_Lymphoma	NLRP8 →	+0.028	+3.130	<.001	.006	3	1
BLOOD_Lymphoma	KRTAP3-3 →	+0.022	+3.662	<.001	.009	3	1
BLOOD_Lymphoma	KRTAP3-2 →	+0.031	+3.662	<.001	.009	3	1
BLOOD_Lymphoma	CLEC5A →	+0.035	+3.142	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

SLC5A1 by ATL2 expression — BLOOD_Lymphoma

Explore this box plot interactively →