Across TCGA patient cohorts, ATL1 mutation is significantly associated with the total protein of many other genes, with 27 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATL1-associated genes across cancer lineages are EGFR_pY1068, MEK1, and ASNS. Each is linked with ATL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATL1-to-partner and partner-to-ATL1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATL1→partner) and Y-score (partner→ATL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	EGFR_pY1068 →	-0.322	-2.906	.002	.001	3	2
UCEC	MEK1 →	+0.444	+2.906	.004	.001	3	2
COAD	ASNS →	+0.991	+3.008	<.001	.019	3	2
COAD	NF2 →	+0.229	+3.008	.023	.019	3	2
COAD	Di-Ras3 →	-0.292	-3.000	.003	.035	3	2
UCEC	EGFR →	-0.166	-3.169	.014	.019	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

Exploration

ATL1 survival (RNA) · tumor vs normal (RNA) · all ATL1 data types