Across TCGA cell cohorts, ATL1 mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ATL1-associated genes across cancer lineages are PTH, FCN2, and CCDC42. Each is linked with ATL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATL1-to-partner and partner-to-ATL1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATL1→partner) and Y-score (partner→ATL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	PTH →	+0.063	+4.684	<.001	.002	3	1
LARGE_INTESTINE	FCN2 →	+0.039	+4.415	<.001	.007	3	1
LARGE_INTESTINE	CCDC42 →	+0.033	+4.095	.008	.009	3	1
LARGE_INTESTINE	HTR1E →	+0.106	+4.930	<.001	.001	3	1
LARGE_INTESTINE	S100G →	+2.043	+4.273	<.001	.006	3	1
LARGE_INTESTINE	MAGEB3 →	+0.055	+4.467	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

ATL1 survival (RNA) · tumor vs normal (RNA) · all ATL1 data types