Across TCGA patient cohorts, ATG7 protein abundance is significantly associated with the RNA expression of many other genes, with 17,057 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ATG7-associated genes across cancer lineages are ITGAM, LILRB4, and FCGR2B. Each is linked with ATG7 in more than 8 cancer types. Because this analysis shows association rather than direction, both ATG7-to-partner and partner-to-ATG7 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATG7→partner) and Y-score (partner→ATG7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ITGAM →	+0.952	+0.290	<.001	<.001	3	9
HNSC	LILRB4 →	+1.258	+0.300	<.001	<.001	3	9
GBM	FCGR2B →	+1.098	+0.247	<.001	<.001	3	9
UCEC	KLHL6 →	+0.897	+0.174	.001	.006	3	8
UCEC	HCLS1 →	+1.190	+0.249	<.001	<.001	3	8
HNSC	CYTH4 →	+1.058	+0.320	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,057 associations by consensus.

Exploration

ATG7 survival (RNA) · tumor vs normal (RNA) · all ATG7 data types