Across TCGA cell cohorts, ATG7 mutation is significantly associated with the RNA expression of many other genes, with 27 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ATG7-associated genes across cancer lineages are HHLA1, RXFP3, and CCT8L2. Each is linked with ATG7 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATG7-to-partner and partner-to-ATG7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATG7→partner) and Y-score (partner→ATG7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	HHLA1 →	+0.011	+4.966	<.001	<.001	3	1
BLOOD_Leukemia	RXFP3 →	+0.014	+3.874	<.001	.005	3	1
BLOOD_Leukemia	CCT8L2 →	+0.009	+3.874	<.001	.005	3	1
BLOOD_Leukemia	C9orf57 →	+0.127	+4.450	<.001	.001	3	1
BLOOD_Leukemia	USP17L1 →	+0.060	+4.133	<.001	.003	3	1
BLOOD_Leukemia	MAGEL2 →	+0.634	+4.133	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 27 associations by consensus.

Exploration

ATG7 survival (RNA) · tumor vs normal (RNA) · all ATG7 data types