Across TCGA cell cohorts, ATG7 mutation is significantly associated with the mutation status of many other genes, with 4,945 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ATG7-associated genes across cancer lineages are NACA, NTRK1, and GABBR2. Each is linked with ATG7 in more than 3 cancer types. Because this analysis shows association rather than direction, both ATG7-to-partner and partner-to-ATG7 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATG7→partner) and Y-score (partner→ATG7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	NACA →	+4.857	+4.297	.009	.009	1	4
STOMACH	NTRK1 →	+4.807	+4.807	.008	.008	1	4
BLOOD_Leukemia	GABBR2 →	+3.285	+3.662	.004	.004	1	4
CNS	WIPI1 →	+6.044	+6.044	.001	.001	1	4
BREAST	ERC2 →	+4.857	+4.297	.009	.009	1	3
BREAST	SCN8A →	+2.857	+4.142	.008	.008	1	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,945 associations by consensus.

Exploration

ATG7 survival (RNA) · tumor vs normal (RNA) · all ATG7 data types