ATG4A

Across TCGA patient cohorts, ATG4A protein abundance is significantly associated with the RNA expression of many other genes, with 7,742 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ATG4A-associated genes across cancer lineages are CXCL1, ZNF853, and DNM1. Each is linked with ATG4A in more than 3 cancer types. Because this analysis shows association rather than direction, both ATG4A-to-partner and partner-to-ATG4A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATG4A versus CXCL1 in OV, with a Pearson correlation of 0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATG4A→partner) and Y-score (partner→ATG4A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CXCL1 →	+1.234	+0.358	.006	<.001	3	3
OV	ZNF853 →	-1.005	-0.452	.006	.007	3	3
UCEC	DNM1 →	-0.713	-0.281	<.001	.001	3	3
COAD	NRXN2 →	-0.497	-0.254	.005	.002	3	3
GBM	ACVR2B →	-0.623	-0.484	<.001	<.001	3	3
BRCA	NAPB →	-0.576	-0.305	.007	.009	2	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,742 associations by consensus.

ATG4A vs CXCL1 — OV

Explore this scatter interactively →