ATG3

Across TCGA patient cohorts, ATG3 protein abundance is significantly associated with the RNA expression of many other genes, with 13,823 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ATG3-associated genes across cancer lineages are CD244, ARHGAP9, and SP140. Each is linked with ATG3 in more than 7 cancer types. Because this analysis shows association rather than direction, both ATG3-to-partner and partner-to-ATG3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATG3 versus CD244 in LUAD, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATG3→partner) and Y-score (partner→ATG3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	CD244 →	+0.560	+0.164	<.001	.009	3	8
HNSC	ARHGAP9 →	+0.800	+0.236	.001	.002	3	8
LUAD	SP140 →	+0.896	+0.241	<.001	<.001	3	8
CCRCC	SIRPG →	+0.965	+0.203	<.001	<.001	3	8
OV	CYTIP →	+1.027	+0.242	<.001	<.001	3	7
OV	CD48 →	+0.984	+0.209	<.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,823 associations by consensus.

ATG3 vs CD244 — LUAD

Explore this scatter interactively →