ATG16L2

Across TCGA cell cohorts, ATG16L2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,610 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ATG16L2-associated GO terms across cancer lineages are Sperm motility, Flagellated sperm motility, and Chiasma assembly. Each is linked with ATG16L2 in more than 15 cancer types. Because this analysis shows association rather than direction, both ATG16L2-to-partner and partner-to-ATG16L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Sperm motility grouped by ATG16L2-low versus ATG16L2-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATG16L2→partner) and Y-score (partner→ATG16L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Sperm motility →	-0.114	-1.684	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	Flagellated sperm motility →	-0.114	-1.684	<.001	<.001	3	16
KIDNEY	Chiasma assembly →	+0.281	+0.995	.001	.005	3	15
OESOPHAGUS	Cilium or flagellum-dependent cell motility →	-0.098	-1.552	<.001	<.001	3	14
OESOPHAGUS	Cilium-dependent cell motility →	-0.098	-1.552	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Cilium movement involved in cell motility →	-0.110	-1.622	<.001	.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,610 associations by consensus.

Sperm motility by ATG16L2 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →