ATG16L1

Across TCGA patient cohorts, ATG16L1 RNA expression is significantly associated with the protein abundance of many other proteins, with 8,846 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ATG16L1-associated proteins across cancer lineages are TRIP12, ATG5, and DTYMK. Each is linked with ATG16L1 in more than 3 cancer types. Because this analysis shows association rather than direction, both ATG16L1-to-partner and partner-to-ATG16L1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATG16L1 versus TRIP12 in LSCC, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ATG16L1→partner) and Y-score (partner→ATG16L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TRIP12 →	+0.284	+0.467	<.001	<.001	3	4
BRCA	ATG5 →	+0.248	+0.611	<.001	.001	3	4
PDAC	DTYMK →	+0.354	+0.398	<.001	<.001	3	4
BRCA	PRDX4 →	-0.400	-0.583	<.001	<.001	3	3
LUAD	AARS1 →	-0.317	-0.477	<.001	<.001	3	3
BRCA	SND1 →	-0.250	-0.589	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,846 associations by consensus.

ATG16L1 vs TRIP12 — LSCC

Explore this scatter interactively →