ATG13

Across TCGA pan-cancer cohorts, ATG13 mass-spec protein differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of ATG13’s most consistent transcriptional readouts.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where ATG13 mass-spec protein is more highly expressed in tumor relative to normal tissue. In most cancer types ATG13 is over-expressed in tumor, although a few such as PDAC show the opposite, repressed pattern.

CCRCC, HNSC, and LSCC are the cancer types where ATG13 tumor–normal differential expression is most reproducible.

mass-spec protein tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in ATG13 mass-spec protein (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
CCRCC	All	IV	+0.311	<.001	9	view →
HNSC	Male	II,III,IV	+0.136	<.001	8	view →
LSCC	Male	All	+0.182	<.001	4	view →
PDAC	All	All	−0.152	.015	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

ATG13–CCRCC

Open the CCRCC breakdown →