ATG13

Across TCGA patient cohorts, ATG13 mutation is significantly associated with the RNA expression of many other genes, with 470 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATG13-associated genes across cancer lineages are LINC02706, RNA5SP55, and RNU6-543P. Each is linked with ATG13 in more than 2 cancer types. Because this analysis shows association rather than direction, both ATG13-to-partner and partner-to-ATG13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC02706 grouped by ATG13-low versus ATG13-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATG13→partner) and Y-score (partner→ATG13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	LINC02706 →	+0.119	+4.733	<.001	.004	3	3
SKCM	RNA5SP55 →	+0.160	+4.475	<.001	.005	3	3
BRCA	RNU6-543P →	+0.283	+8.055	<.001	.007	3	3
BRCA	USP9YP2 →	+0.044	+7.731	<.001	.009	3	3
CESC	LINC01999 →	+0.112	+3.870	<.001	.002	3	2
CESC	RNU6-271P →	+0.156	+4.837	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 470 associations by consensus.

LINC02706 by ATG13 expression — LUSC

Explore this box plot interactively →