ATG13

Across TCGA cell cohorts, ATG13 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,330 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ATG13-associated GO terms across cancer lineages are Response to mitochondrial depolarisation, Protein polyubiquitination, and Negative regulation of autophagy. Each is linked with ATG13 in more than 18 cancer types. Because this analysis shows association rather than direction, both ATG13-to-partner and partner-to-ATG13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to mitochondrial depolarisation grouped by ATG13-low versus ATG13-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATG13→partner) and Y-score (partner→ATG13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Response to mitochondrial depolarisation →	+0.157	+1.085	<.001	<.001	3	19
STOMACH	Protein polyubiquitination →	+0.075	+0.858	<.001	.001	3	15
STOMACH	Negative regulation of autophagy →	+0.117	+0.998	<.001	<.001	2	15
LUNG_NSCLC_LUSC	Autophagy of mitochondrion →	+0.077	+0.885	<.001	<.001	3	14
KIDNEY	Process utilizing autophagic mechanism →	+0.065	+0.918	<.001	<.001	3	14
KIDNEY	Autophagy →	+0.065	+0.918	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,330 associations by consensus.

Response to mitochondrial depolarisation by ATG13 expression — URINARY_TRACT

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