ATG13

Across TCGA cell cohorts, ATG13 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ATG13-associated genes across cancer lineages are PABPC1L2B, MAGEB4, and HSFY2. Each is linked with ATG13 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATG13-to-partner and partner-to-ATG13 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PABPC1L2B grouped by ATG13-low versus ATG13-high in UPPER_AERODIGESTIVE_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATG13→partner) and Y-score (partner→ATG13) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	PABPC1L2B →	+0.099	+4.736	.009	.009	3	1
LARGE_INTESTINE	MAGEB4 →	+0.012	+5.415	.009	.004	3	1
LARGE_INTESTINE	HSFY2 →	+0.023	+4.977	<.001	.007	3	1
LARGE_INTESTINE	HSFY1 →	+0.026	+5.415	<.001	.004	3	1
LARGE_INTESTINE	AMELY →	+0.060	+6.022	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

PABPC1L2B by ATG13 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →