ATG12

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ATG12 mutation is significantly associated with the immune_cell of many other genes, with 1 significant associations in total. LUSC shows the largest number of these associations.

The most reproducible ATG12-associated genes across cancer lineages are Eosinophils. Each is linked with ATG12 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATG12-to-partner and partner-to-ATG12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Eosinophils grouped by ATG12-low versus ATG12-high in LUSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATG12→partner) and Y-score (partner→ATG12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUSCEosinophils →+0.049+3.173<.001.04931
Each partner links to its Q-omics profile. Showing the 1 strongest of 1 associations by consensus.

Eosinophils by ATG12 expression — LUSC

Box plot of Eosinophils in ATG12-low vs ATG12-high samples in LUSC.

Explore this box plot interactively →

Exploration