ATG12

Across TCGA cell cohorts, ATG12 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,048 significant associations in total. BONE shows the largest number of these associations.

The most reproducible ATG12-associated GO terms across cancer lineages are Regulation of centriole elongation, Endoplasmic reticulum to Golgi vesicle-mediated transport, and Nuclear membrane organization. Each is linked with ATG12 in more than 15 cancer types. Because this analysis shows association rather than direction, both ATG12-to-partner and partner-to-ATG12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of centriole elongation grouped by ATG12-low versus ATG12-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATG12→partner) and Y-score (partner→ATG12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Regulation of centriole elongation →	+0.106	+0.779	.001	.003	3	16
SOFT_TISSUE	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.075	+0.483	<.001	<.001	3	14
BREAST	Nuclear membrane organization →	+0.074	+0.640	<.001	.001	3	13
SKIN	Interkinetic nuclear migration →	+0.101	+0.559	<.001	<.001	3	12
OVARY	Clathrin-coated vesicle cargo loading →	+0.139	+0.756	<.001	<.001	3	12
OVARY	Clathrin-coated vesicle cargo loading, AP-3-mediated →	+0.139	+0.756	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,048 associations by consensus.

Regulation of centriole elongation by ATG12 expression — STOMACH

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