ATF2

Across TCGA patient cohorts, ATF2 RNA expression is significantly associated with the protein abundance of many other proteins, with 12,930 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible ATF2-associated proteins across cancer lineages are KDM1A, ORC3, and CDC73. Each is linked with ATF2 in more than 4 cancer types. Because this analysis shows association rather than direction, both ATF2-to-partner and partner-to-ATF2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATF2 versus KDM1A in LSCC, with a Pearson correlation of 0.44.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ATF2→partner) and Y-score (partner→ATF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	KDM1A →	+0.351	+0.431	<.001	<.001	3	5
GBM	ORC3 →	+0.307	+0.299	.001	.001	3	5
GBM	CDC73 →	+0.230	+0.260	.004	.008	3	5
LSCC	ZNF638 →	+0.266	+0.343	<.001	<.001	3	4
HNSC	ZNF638_S128 →	+0.464	+0.516	<.001	<.001	3	4
HNSC	RCOR3 →	+0.366	+0.376	<.001	.006	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,930 associations by consensus.

ATF2 vs KDM1A — LSCC

Explore this scatter interactively →