ATF2

Across TCGA cell cohorts, ATF2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,428 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ATF2-associated GO terms across cancer lineages are Medulla oblongata development, Positive regulation of organelle assembly, and Brainstem development. Each is linked with ATF2 in more than 18 cancer types. Because this analysis shows association rather than direction, both ATF2-to-partner and partner-to-ATF2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Medulla oblongata development grouped by ATF2-low versus ATF2-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATF2→partner) and Y-score (partner→ATF2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Medulla oblongata development →	+0.332	+0.770	.002	<.001	3	19
LUNG_NSCLC_LUSC	Positive regulation of organelle assembly →	+0.068	+0.801	<.001	<.001	3	17
LUNG_SCLC	Brainstem development →	+0.232	+0.901	<.001	<.001	3	17
LUNG_SCLC	Pons development →	+0.155	+0.804	<.001	<.001	3	16
SKIN	Growth plate cartilage chondrocyte proliferation →	+0.206	+0.577	<.001	<.001	3	16
LUNG_NSCLC_LUSC	Regulation of endoplasmic reticulum tubular network organization →	+0.142	+1.065	.009	.002	2	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,428 associations by consensus.

Medulla oblongata development by ATF2 expression — BREAST

Explore this box plot interactively →