ATF1

Across TCGA pan-cancer cohorts, ATF1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated ATF1 data layer compared with 24 for mass-spec protein and 4 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher ATF1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated ATF1 expression acts as an unfavorable survival marker.

LUAD, UCEC, and LSCC are the cancer types where ATF1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Tertile	II,III,IV	0.750	0.966	.001	24	view →
UCEC	DFS	Median	II,III,IV	0.530	0.877	.019	12	view →
LSCC	DFS	Median	III,IV	0.450	0.910	.015	10	view →
PDAC	DFS	Median	IV	0.251	0.934	.038	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

ATF1–LUAD (DFS)

Open the LUAD breakdown →