ATF1

Across TCGA cell cohorts, ATF1 protein abundance is significantly associated with the go_rna of many other GO terms, with 348 significant associations in total. KIDNEY shows the largest number of these associations.

The most reproducible ATF1-associated GO terms across cancer lineages are Response to axon injury, Positive regulation of telomere capping, and Neuron cell-cell adhesion. Each is linked with ATF1 in more than 2 cancer types. Because this analysis shows association rather than direction, both ATF1-to-partner and partner-to-ATF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Response to axon injury grouped by ATF1-low versus ATF1-high in LARGE_INTESTINE.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATF1→partner) and Y-score (partner→ATF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Response to axon injury →	+0.096	+1.374	.003	.004	3	3
LUNG_NSCLC_LUAD	Positive regulation of telomere capping →	-0.116	-1.632	<.001	.005	3	3
LUNG_NSCLC_LUAD	Neuron cell-cell adhesion →	+1.781	+2.262	<.001	<.001	3	2
LUNG_NSCLC_LUAD	Negative regulation of intracellular protein transport →	-0.121	-1.909	<.001	.001	3	2
LUNG_NSCLC_LUAD	Nucleoside diphosphate biosynthetic process →	-0.221	-1.734	.005	.009	3	2
LUNG_NSCLC_LUAD	Ribonucleoside diphosphate biosynthetic process →	-0.214	-2.150	.007	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 348 associations by consensus.

Response to axon injury by ATF1 expression — LARGE_INTESTINE

Explore this box plot interactively →