ATE1

Across TCGA patient cohorts, ATE1 protein abundance is significantly associated with the RNA expression of many other genes, with 16,528 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible ATE1-associated genes across cancer lineages are NSMCE4A, ASPA, and SLC43A3. Each is linked with ATE1 in more than 6 cancer types. Because this analysis shows association rather than direction, both ATE1-to-partner and partner-to-ATE1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATE1 versus NSMCE4A in OV, with a Pearson correlation of 0.44.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATE1→partner) and Y-score (partner→ATE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	NSMCE4A →	+0.484	+0.382	<.001	<.001	3	7
CCRCC	ASPA →	+1.064	+0.163	.001	.005	3	6
BRCA	SLC43A3 →	-0.721	-0.235	<.001	<.001	3	6
UCEC	DIO3OS →	+0.565	+0.172	<.001	<.001	3	6
BRCA	ANAPC16 →	+0.498	+0.344	<.001	<.001	3	6
GBM	HSPA6 →	-1.093	-0.210	.005	.006	2	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,528 associations by consensus.

ATE1 vs NSMCE4A — OV

Explore this scatter interactively →