ATCAY

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ATCAY RNA expression is significantly associated with the protein abundance of many other proteins, with 11,343 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ATCAY-associated proteins across cancer lineages are GUCY1B1, TNS2, and SEPTIN4. Each is linked with ATCAY in more than 4 cancer types. Because this analysis shows association rather than direction, both ATCAY-to-partner and partner-to-ATCAY results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATCAY versus GUCY1B1 in GBM, with a Pearson correlation of 0.48.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (ATCAY→partner) and Y-score (partner→ATCAY) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMGUCY1B1 →+0.362+1.365<.001<.00135
HNSCTNS2 →+0.283+0.203<.001<.00134
PDACSEPTIN4 →+0.503+0.198<.001<.00134
COADKANK2 →+0.484+0.061<.001<.00134
HNSCMAP1A →+0.445+0.230<.001.00434
HNSCSYNPO →+0.681+0.215<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 11,343 associations by consensus.

ATCAY vs GUCY1B1 — GBM

Per-sample scatter of ATCAY vs GUCY1B1 in GBM (Pearson r = 0.48).

Explore this scatter interactively →

Exploration