ATCAY

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ATCAY protein abundance is significantly associated with the RNA expression of many other genes, with 3,494 significant associations in total. GBM shows the largest number of these associations.

The most reproducible ATCAY-associated genes across cancer lineages are YPEL1, SNRPD3, and GRK3. Each is linked with ATCAY in more than 1 cancer types. Because this analysis shows association rather than direction, both ATCAY-to-partner and partner-to-ATCAY results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATCAY versus YPEL1 in GBM, with a Pearson correlation of 0.31.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATCAY→partner) and Y-score (partner→ATCAY) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMYPEL1 →+0.538+0.531.001<.00131
GBMSNRPD3 →+0.498+0.725<.001<.00131
GBMGRK3 →+0.384+0.443.005.00131
GBMSEZ6L →+1.631+0.503<.001<.00131
GBMPOLR2F →+0.454+0.413.002.00231
GBMSOX10 →+1.260+0.539<.001<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,494 associations by consensus.

ATCAY vs YPEL1 — GBM

Per-sample scatter of ATCAY vs YPEL1 in GBM (Pearson r = 0.31).

Explore this scatter interactively →

Exploration