ATAD5

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ATAD5 protein abundance is significantly associated with the RNA expression of many other genes, with 7,813 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible ATAD5-associated genes across cancer lineages are MXD4, APOBEC3A, and DYSF. Each is linked with ATAD5 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATAD5-to-partner and partner-to-ATAD5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, ATAD5 versus MXD4 in PDAC, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATAD5→partner) and Y-score (partner→ATAD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
PDACMXD4 →-0.492-0.488<.001.00432
GBMAPOBEC3A →+1.805+1.153.007<.00132
GBMDYSF →+1.126+0.912<.001<.00132
PDACSCN7A →-1.249-0.667.004.00332
GBMLMO4 →-1.153-0.996<.001.00232
PDACSELENBP1 →-1.181-0.664.002.00432
Each partner links to its Q-omics profile. Showing the 6 strongest of 7,813 associations by consensus.

ATAD5 vs MXD4 — PDAC

Per-sample scatter of ATAD5 vs MXD4 in PDAC (Pearson r = -0.38).

Explore this scatter interactively →

Exploration