ATAD5

Across TCGA cell cohorts, ATAD5 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,268 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible ATAD5-associated GO terms across cancer lineages are Regulation of G2/M transition of mitotic cell cycle, Negative regulation of cell cycle process, and Regulation of cell cycle G2/M phase transition. Each is linked with ATAD5 in more than 19 cancer types. Because this analysis shows association rather than direction, both ATAD5-to-partner and partner-to-ATAD5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of G2/M transition of mitotic cell cycle grouped by ATAD5-low versus ATAD5-high in BLOOD_Myeloma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATAD5→partner) and Y-score (partner→ATAD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Regulation of G2/M transition of mitotic cell cycle →	+0.079	+1.393	<.001	<.001	3	20
BONE	Negative regulation of cell cycle process →	+0.097	+1.307	.001	.001	3	20
BONE	Regulation of cell cycle G2/M phase transition →	+0.068	+1.007	.009	.002	3	20
URINARY_TRACT	DNA strand elongation →	+0.154	+1.237	<.001	<.001	3	20
PANCREAS	DNA biosynthetic process →	+0.082	+0.956	<.001	<.001	3	20
LIVER	Double-strand break repair via homologous recombination →	+0.079	+0.944	.002	<.001	3	20

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,268 associations by consensus.

Regulation of G2/M transition of mitotic cell cycle by ATAD5 expression — BLOOD_Myeloma

Explore this box plot interactively →