ATAD5

Across TCGA cell cohorts, ATAD5 mutation is significantly associated with the RNA expression of many other genes, with 1,502 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ATAD5-associated genes across cancer lineages are C1QC, INTS10, and RPA2. Each is linked with ATAD5 in more than 1 cancer types. Because this analysis shows association rather than direction, both ATAD5-to-partner and partner-to-ATAD5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C1QC grouped by ATAD5-low versus ATAD5-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATAD5→partner) and Y-score (partner→ATAD5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	C1QC →	+0.024	+3.196	<.001	.007	3	2
LARGE_INTESTINE	INTS10 →	+0.693	+3.850	<.001	<.001	3	2
LARGE_INTESTINE	RPA2 →	+0.528	+2.459	.002	.006	3	2
LARGE_INTESTINE	SDC4 →	-0.980	-3.169	.008	.009	3	2
LARGE_INTESTINE	XPO7 →	+0.589	+2.743	.004	.001	3	2
LARGE_INTESTINE	FANCD2 →	+0.690	+2.043	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,502 associations by consensus.

C1QC by ATAD5 expression — SKIN

Explore this box plot interactively →