ATAD3B

Across TCGA cell cohorts, ATAD3B RNA expression is significantly associated with the go_rna of many other GO terms, with 4,314 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible ATAD3B-associated GO terms across cancer lineages are Positive regulation of transcription of nucleolar large rRNA by RNA polymerase I, Ribosomal large subunit assembly, and DNA replication proofreading. Each is linked with ATAD3B in more than 17 cancer types. Because this analysis shows association rather than direction, both ATAD3B-to-partner and partner-to-ATAD3B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of transcription of nucleolar large rRNA by RNA polymerase I grouped by ATAD3B-low versus ATAD3B-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATAD3B→partner) and Y-score (partner→ATAD3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	Positive regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.160	+1.366	<.001	<.001	3	18
BLOOD_Lymphoma	Ribosomal large subunit assembly →	+0.127	+1.444	<.001	<.001	3	18
OESOPHAGUS	DNA replication proofreading →	+0.208	+1.322	.002	<.001	3	18
BONE	Regulation of DNA-templated DNA replication →	+0.112	+1.474	<.001	<.001	3	17
BONE	Regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.146	+1.236	<.001	<.001	3	17
KIDNEY	Regulation of telomerase RNA localization to Cajal body →	+0.110	+1.281	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,314 associations by consensus.

Positive regulation of transcription of nucleolar large rRNA by RNA polymerase I by ATAD3B expression — URINARY_TRACT

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