ATAD3B

Across TCGA cell cohorts, ATAD3B mutation is significantly associated with the RNA expression of many other genes, with 13 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible ATAD3B-associated genes across cancer lineages are OPRPN, CSN3, and ANKRD34C. Each is linked with ATAD3B in more than 1 cancer types. Because this analysis shows association rather than direction, both ATAD3B-to-partner and partner-to-ATAD3B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OPRPN grouped by ATAD3B-low versus ATAD3B-high in URINARY_TRACT.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATAD3B→partner) and Y-score (partner→ATAD3B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	OPRPN →	+0.060	+5.087	<.001	.004	3	1
SKIN	CSN3 →	+1.278	+3.920	<.001	.005	3	1
SKIN	ANKRD34C →	+0.035	+3.914	.004	.005	3	1
STOMACH	HES3 →	+0.125	+4.285	<.001	.007	3	1
STOMACH	OR6X1 →	+0.017	+4.285	<.001	.007	3	1
LARGE_INTESTINE	SLAMF8 →	+0.149	+4.132	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 13 associations by consensus.

OPRPN by ATAD3B expression — URINARY_TRACT

Explore this box plot interactively →