ATAD3A

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, ATAD3A mutation is significantly associated with the RNA expression of many other genes, with 1,375 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible ATAD3A-associated genes across cancer lineages are SAR1B, TYW3, and LEO1. Each is linked with ATAD3A in more than 1 cancer types. Because this analysis shows association rather than direction, both ATAD3A-to-partner and partner-to-ATAD3A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATAD3A→partner) and Y-score (partner→ATAD3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECSAR1B →+0.453+3.024<.001<.00132
UCECTYW3 →+0.434+1.955.001.00832
UCECLEO1 →+0.392+2.831.006.00132
UCECZBTB8OS →+0.391+3.732<.001<.00132
UCECPSMA4 →+0.461+2.906<.001<.00132
UCECMSANTD3 →+0.448+2.016.003.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,375 associations by consensus.

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