Across TCGA cell cohorts, ATAD3A mutation is significantly associated with the RNA expression of many other genes, with 176 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible ATAD3A-associated genes across cancer lineages are DEFA4, CCDC182, and PNLIP. Each is linked with ATAD3A in more than 1 cancer types. Because this analysis shows association rather than direction, both ATAD3A-to-partner and partner-to-ATAD3A results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (ATAD3A→partner) and Y-score (partner→ATAD3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	DEFA4 →	+0.056	+5.977	<.001	.001	3	1
LUNG_SCLC	CCDC182 →	+0.055	+3.070	.004	.009	3	1
LUNG_SCLC	PNLIP →	+0.111	+3.684	<.001	.001	3	1
LUNG_SCLC	HMGB4 →	+0.041	+4.058	<.001	.001	3	1
LUNG_SCLC	FIGLA →	+0.139	+3.781	<.001	.003	3	1
OVARY	DRD3 →	+0.013	+3.990	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 176 associations by consensus.

Exploration

ATAD3A survival (RNA) · tumor vs normal (RNA) · all ATAD3A data types