ATAD1

Across TCGA cell cohorts, ATAD1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,049 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ATAD1-associated GO terms across cancer lineages are Negative regulation of synaptic transmission, glutamatergic, ERAD pathway, and Regulation of sister chromatid cohesion. Each is linked with ATAD1 in more than 11 cancer types. Because this analysis shows association rather than direction, both ATAD1-to-partner and partner-to-ATAD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of synaptic transmission, glutamatergic grouped by ATAD1-low versus ATAD1-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ATAD1→partner) and Y-score (partner→ATAD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Negative regulation of synaptic transmission, glutamatergic →	+0.526	+1.436	.007	.008	3	12
LARGE_INTESTINE	ERAD pathway →	+0.063	+0.589	.002	.005	3	11
LUNG_NSCLC_LUSC	Regulation of sister chromatid cohesion →	+0.169	+0.675	<.001	<.001	3	10
UPPER_AERODIGESTIVE_TRACT	Viral translational termination-reinitiation →	+0.077	+0.728	.002	<.001	3	10
OVARY	Endoplasmic reticulum to Golgi vesicle-mediated transport →	+0.061	+0.560	.007	.009	3	10
URINARY_TRACT	Endoplasmic reticulum mannose trimming →	+0.125	+0.755	<.001	.003	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,049 associations by consensus.

Negative regulation of synaptic transmission, glutamatergic by ATAD1 expression — SKIN

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