ASTN1

Across TCGA cell cohorts, ASTN1 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,031 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible ASTN1-associated GO terms across cancer lineages are Protein exit from endoplasmic reticulum, Cytoplasmic translation, and Regulation of myoblast fusion. Each is linked with ASTN1 in more than 6 cancer types. Because this analysis shows association rather than direction, both ASTN1-to-partner and partner-to-ASTN1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein exit from endoplasmic reticulum grouped by ASTN1-low versus ASTN1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ASTN1→partner) and Y-score (partner→ASTN1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Protein exit from endoplasmic reticulum →	+0.087	+0.569	<.001	.009	3	6
LUNG_SCLC	Cytoplasmic translation →	+0.075	+1.298	.007	.004	1	7
LUNG_SCLC	Regulation of myoblast fusion →	+0.070	+1.121	<.001	<.001	3	5
LUNG_SCLC	Negative regulation of myoblast fusion →	+0.074	+1.042	<.001	<.001	3	5
LUNG_SCLC	Regulation of mRNA stability →	+0.037	+1.133	<.001	<.001	3	5
LUNG_SCLC	Regulation of syncytium formation by plasma membrane fusion →	+0.071	+1.161	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,031 associations by consensus.

Protein exit from endoplasmic reticulum by ASTN1 expression — SOFT_TISSUE

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