Across TCGA patient cohorts, ASTL RNA expression is significantly associated with the go_rna of many other GO terms, with 7,154 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible ASTL-associated GO terms across cancer lineages are Viral gene expression, Viral transcription, and Epigenetic regulation of gene expression. Each is linked with ASTL in more than 23 cancer types. Because this analysis shows association rather than direction, both ASTL-to-partner and partner-to-ASTL results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ASTL→partner) and Y-score (partner→ASTL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LAML	Viral gene expression →	+0.040	+0.579	<.001	<.001	3	24
PAAD	Viral transcription →	+0.046	+0.265	<.001	<.001	3	23
STAD	Epigenetic regulation of gene expression →	+0.051	+0.224	<.001	.002	3	23
UCS	Positive regulation of intracellular transport →	+0.047	+1.050	<.001	<.001	3	23
STAD	Immune system development →	+0.047	+0.223	<.001	.002	3	22
STAD	Cellular response to UV →	+0.048	+0.231	<.001	.001	2	23

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,154 associations by consensus.

Exploration

ASTL survival (RNA) · tumor vs normal (RNA) · all ASTL data types