Across TCGA cell cohorts, ASTL RNA expression is significantly associated with the go_rna of many other GO terms, with 1,390 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible ASTL-associated GO terms across cancer lineages are Regulation of macroautophagy, Positive regulation of nucleocytoplasmic transport, and Positive regulation of nuclear-transcribed mRNA poly(A) tail shortening. Each is linked with ASTL in more than 4 cancer types. Because this analysis shows association rather than direction, both ASTL-to-partner and partner-to-ASTL results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (ASTL→partner) and Y-score (partner→ASTL) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Regulation of macroautophagy →	+0.048	+0.239	<.001	.007	3	5
STOMACH	Positive regulation of nucleocytoplasmic transport →	+0.081	+0.392	<.001	<.001	3	5
BLOOD_Lymphoma	Positive regulation of nuclear-transcribed mRNA poly(A) tail shortening →	+0.096	+0.646	<.001	<.001	3	5
CNS	Regulation of fertilization →	-0.128	-0.165	.005	.009	3	5
UPPER_AERODIGESTIVE_TRACT	Regulation of mRNA catabolic process →	+0.042	+0.066	<.001	.003	3	4
LUNG_NSCLC_LUAD	Regulation of RNA stability →	+0.020	+0.109	<.001	.006	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,390 associations by consensus.

Exploration

ASTL survival (RNA) · tumor vs normal (RNA) · all ASTL data types