Across TCGA pan-cancer cohorts, ASS1P4 RNA is linked to patient survival in 8 of 34 cancer types, making it the most broadly survival-associated ASS1P4 data layer.
The strongest signal is observed in breast invasive carcinoma (BRCA), where higher ASS1P4 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated ASS1P4 expression acts as an unfavorable survival marker, although some lineages such as KIRC show a favorable association.
BRCA, UCEC, and UVM are the cancer types where ASS1P4 RNA most reproducibly stratifies survival.
RNA survival associations by lineage
Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.